Enzymatic cleaner for endoscopes and surgical instruments

NOSOZYM is a very efficient concentrated enzymatic cleaner for surgical instruments and endoscopes.

NOSOZYM has a neutral pH and contains a combination of enzymes (protease, lipase, amylase) that degrade proteins, fats, and blood residues. It drastically removes organic residues and prevents corrosion and instruments discoloration. It removes even the toughest deposits.

It is suitable for the cleaning in ultrasonic bath, in automated endoscope washer – disinfectors, in instrument washers, in immersion bath or by conventional hand washing.

NOSOZYM is compatible with OLYMPUS ®, KARL STORZ ® and PENTAX MEDICAL ® endoscopes.


  • Combination of enzymes for an enhanced cleaning action
  • Drastically removes organic residues
  • Very economical: Up to 0,5% dilution
  • Suitable for the cleaning in ultrasonic bath, in instrument washers, in immersion bath, by conventional hand washing as well as in automated endoscope disinfectors
  • Does not foam, prevents corrosion and instrument discoloration
  • Appropriate for heat-resistant as well as heat-sensitive instruments


NOSOΖΥΜ is compatible with most materials such as stainless steel, aluminum, glass, ceramics, hard plastics, ebonite, etc …

Ultrasonic bath

ΝΟSΟΖΥΜ can be used in all common types of ultrasonic baths. it can be used at 0,5% dilution.

Endoscopes - cleaning with enzymes

Cleaning is the critical step in endoscopes reprocessing.

Endoscope cleaning consists of the mechanical cleaning of internal and external surfaces. This includes brushing and flushing of internal channels with sterile, filtered or drinking-quality water and detergent. The purpose of cleaning is to remove all inorganic and organic material from the internal and external surfaces of flexible endoscopes.

If the manual cleaning, brushing and rinsing steps are not properly carried out, protein debris can harden and lead to formation of biofilm on the biopsy channel of the endoscope. Inadequate cleaning can thus result in material remaining on the endoscope surfaces which prevents disinfection and sterilization fluids or gases reaching all parts of potentially contaminated surfaces.

The endoscope should be cleaned with an enzymatic cleaner immediately after use and before manual or automated disinfection.

NOSOZYM contains a combination of specific enzymes. The enzymes break down the soil into tiny fragments, making it water soluble and thus easier to remove by rinsing.

Use NOSOZYM for endoscope cleaning:

  • by manual cleaning at a dilution up to 0,5%
  • in automated reprocessor at a dilution up to 0,5% (follow the manufacturer instructions)
NOSOZYM - Enzymatic detergent for surgical instruments and endoscope


  • 5 litre canister (Ref. 20022)
  • Dosing pump for 5 litre canister (Ref. 20023)

Physical properties

  • Appearance: Light yellow solution
  • Density: 1.02 g/cm3 at 20˚C
  • pH: 7.0 – 8.0 (Neutral) at 20˚C
  • pH (0.2% – 1%): 7.0 – 8.0 (Neutral) at 20˚C
  • Odour: Neutral
  • Storage: 5˚C – 35˚C
  • Stability: 3 Years
  • Biodegradability: According to OCDE 301D


Protease, lipase, amylase, non ionic surfactants <5%, corrosion inhibitor, pH regulator, excipients.

NOSOZYM is manufactured in Greece. MEDALKAN satisfies the requirements of ISO 9001 for quality management system and the requirements of ISO 13485 for the design and manufacture of medical devices.

ISO Certification
  • Approved by the General Chemical State Laboratory
  • CE mark according to the medical devices Directive (Directive 93/42/EEC)
  • Medical device class I